The relationship clinicopathology differentiated thyroid carcinoma post thyroidectomy on scintigraphy profile

Abstract

Introduction: Differentiated thyroid carcinoma (DTC) is one of the most frequently found endocrine malignancies. This study was conducted to evaluate the factors responsible for the presence of residual thyroid tissue in scintigraphy.

Methods: Retrospective study of patients with DTC identified from the Medical records. Statistical analysis included standardized differences, P values, and chi-square test was used to compare each difference variables; a P value of < 0.05 was considered to have statistical significance.

Results: 112 patients with DTC who underwent near-total or total thyroidectomy mean age 43,4 ± 16.0 (standard deviation) years, 94 (83,9%) female, 25,18 (16,1%) male. The average tumor size with well-differentiated thyroid carcinoma was 5.5 ± 1.6 cm. All patients were not found to have metastasis. 97 patients showed residual thyroid tissue after surgery on scintigraphy examination. Tumor size ≥ 5 cm, p = 0.32. Well differentiated thyroid carcinoma showed residual thyroid tissue after thyroidectomy on scintigraphy, p = 0.28. Residual thyroid tissue in group 1 and group 2, p = 0.98. Residual thyroid tissue with major capsular invasion, p = 0.17. Patients undergoing near total thyroidectomy, p = 0.65. Low risk group, p = 0.002.

Conclusion: Residual thyroid tissue posts near-total or total thyroidectomy is significantly associated with high-risk groups patients well-differentiated thyroid carcinoma.